Sequences homologous to variant antigen mRNA spliced leader in Trypanosomatidae which do not undergo antigenic variation.

doi:10.1038/308665a0

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Article

Sequences homologous to variant antigen mRNA spliced leader in Trypanosomatidae which do not undergo antigenic variation.

Nature - 1 Jan 2000

Nelson R G, Parsons M, Selkirk M, Newport G, Barr P J, Agabian N

Abstract excerpt

Trypanosomes which parasitize mammals have evolved mechanisms to evade immune attack, such as the occupation of 'safe' intracellular sites (for example, Trypanosoma cruzi), or antigenic variation, exemplified by the salivarian trypanosomes (for example, Trypanosoma brucei). Antigenic variation is...

Topics

Animals
Base Sequence
Genes
Genetic Variation
Glycoproteins
RNA Splicing
RNA, Messenger
Species Specificity
Trypanosoma
Variant Surface Glycoproteins, Trypanosoma

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