Normal male carriers in the fra(X) form of X-linked mental retardation (Martin-Bell syndrome).

doi:10.1002/ajmg.1320230156

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Article

Normal male carriers in the fra(X) form of X-linked mental retardation (Martin-Bell syndrome).

American journal of medical genetics - 1 Jan 2000

Froster-Iskenius U, McGillivray B C, Dill F J, Hall J G, Herbst D S

Abstract excerpt

Evidence for the transmission of X-linked mental retardation through normal male carriers is reviewed in 6 kindreds. In these pedigrees we identified 15 unaffected males who likely had passed the gene on through their daughters. Fifty-one mentally retarded grandsons or great grandsons descended f...

Topics

Female
Fragile X Syndrome
Heterozygote
Humans
Intellectual Disability
Intelligence
Male
Pedigree
Phenotype
Risk
Sex Chromosome Aberrations

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