Formal genetics of isoniazid metabolism in man.

doi:10.2165/00003088-198308060-00005

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Article

Formal genetics of isoniazid metabolism in man.

Clinical pharmacokinetics - 1 Jan 2000

Iselius L, Evans D A

Abstract excerpt

Complex segregation analysis of the isoniazid inactivator phenotype has shown the existence of a recessive gene and a multifactorial background. The phenotype is also influenced by age, sex and weight. The relevance of these findings to the grouping of individuals into slow and rapid inactivators is stressed.

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PMID: 6653034
DOI: 10.2165/00003088-198308060-00005

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