Article
Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells.
Nature - 1 Jan 2000
Miesfeld R, Okret S, Wikström A C, Wrange O, Gustafsson J A, Yamamoto K R
Abstract excerpt
The effects of steroid hormones are mediated by intracellular hormone-specific receptor proteins; the interaction between the hormone and its receptor increases the affinity of the receptor for nuclear binding sites, thereby modulating the expression of specific genes. The glucocorticoid receptor...
Topics
- Animals
- Cell Line
- Cloning, Molecular
- DNA
- Fibroblasts
- Gene Expression Regulation
- Genes
- Liver
- Lymphoma
- Molecular Weight
- Mutation
- RNA, Messenger
- Rats
- Receptors, Glucocorticoid
- Receptors, Steroid