Article
[Mutant gene expression in mouse aggregation chimeras. 3. The brachypodism-H gene].
Ontogenez - 1 Jan 2000
Malinina N A, Kindiakov B N, Koniukhov B V
Abstract excerpt
The expression of gene brachypodism-H (bpH) was studied on the 12-, 14-, 16-, 17-, 19-day old embryos and 20-day old bpH/bpH C/C----+/+ c + c mice. In 18 chimaeras, the percentage of pigmented cells in the retinal pigment epithelium varied from 2.5 to 84.0%, suggesting a different proportion of the mutant and normal cells in their tissues. The limb development was quite normal in all chimaeras: even in the...
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