Article
Immune regulation and HLA types in chronic hepatitis.
Hepatology (Baltimore, Md.) - 1 Jan 2000
Krawitt E L, Albertini R J, Webb D D, Chastenay B F, Holdstock G, MacPherson B R
Abstract excerpt
Studies were undertaken in 32 patients with hepatitis B-negative or -positive chronic active hepatitis or chronic persistent hepatitis to define the relationship between immunoregulatory activity and the HLA-B8 and B12 phenotypes. Suppressor T-cell activity measured by a concanavalin A-induced suppressor system using allogeneic responder cells was dependent on which individual was selected as a source of...
Topics
- Adult
- Aged
- Chronic Disease
- Concanavalin A
- Female
- HLA Antigens
- Hepatitis
- Histocompatibility Antigens Class II
- Humans
- Male
- Middle Aged
- Phenotype