Article
Comparisons of peripheral blood and hepatic lymphocyte subpopulations and interferon production in chronic viral hepatitis.
Journal of clinical & laboratory immunology - 1 Sept 1990
Kakumu S, Yoshioka K, Wakita T, Ishikawa T, Murase K, Kusakabe A, Kurokawa S
Abstract excerpt
Studies were undertaken to clarify the immunological mechanism in patients with chronic hepatitis C compared with chronic hepatitis B. Phenotypic study by flow cytometry showed that CD8+ T cells and HLA-DR+ cells isolated from liver biopsy specimen were significantly increased in their proportions as compared with those in peripheral blood, while intrahepatic CD4+ T cells were significantly lower than peripheral...
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