Article
A biochemical analysis of the secregation of HLA-DR heavy and light chains in a family studied by two-dimensional gel electrophoresis.
Annales d'immunologie - 1 Jan 2000
Roux-Dosseto M, Rohner C, Birnbaum D, Bourgue F, Rebai N, Mawas C, Goridis C
Abstract excerpt
Previous studies in our laboratory using primed lymphocyte typing (PLT) in an informative family have led to the identification of four traits and two regions, separable by recombination within the HLA-DR system. In the present study, we analysed the heterogeneity of HLA-DR antigens among members...
Topics
- Animals
- Antibodies, Monoclonal
- B-Lymphocytes
- Cell Line
- Cross Reactions
- Electrophoresis, Polyacrylamide Gel
- Genes, MHC Class II
- Genotype
- HLA-DR Antigens
- Histocompatibility Antigens Class II
- Humans
- Mice
- Polymorphism, Genetic
- Rabbits