Article
Studies on tolerance development in inbred and heterogeneous stock National Institutes of Health rats.
Alcoholism, clinical and experimental research - 1 Jan 2000
Tabakoff B, Culp S G
Abstract excerpt
The rate of development of environment-independent tolerance was assessed in seven inbred strains of rats, in randomly bred Sprague-Dawley rats, and in the heterogeneous stock (HS) animals developed from the inbred strains. The results demonstrated significant differences in rates of tolerance development between the various groups of inbred animals. A relationship between the initial sensitivity of an animal to...
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