[Simulation of the effects of radiation injury of DNA and genetic hazards of radionuclide decay. Dehydration of purine nucleotides during decay of an incorporated tritium].

Abstract excerpt

The dehydrogenation of purine nucleotides in position 8 is not a severe lethal injury. In addition, the dehydrogenation in the eight position of adenine is not an effective mutagenic event. The dehydrogenation in the eight position of guanine is a mutagenic damage. As to the induction of point mutations, 3H is not more hazardous than external gamma-radiation delivered in equivalent doses.

Topics

• DNA, Fungal
• Gamma Rays
• Genes, Fungal
• Mutation
• Purine Nucleotides
• Saccharomyces cerevisiae
• Tritium