Article
[Modeling the effects of radiation damage to DNA and the genetic risk of radionuclide decay. Dehydrogenation of pyrimidine nucleotides during decay of incorporated 3H].
Radiobiologiia - 1 Jan 2000
Korolev V G, Ivanov E L
Abstract excerpt
Dehydrogenation of DNA pyrimidine nucleotides in thymine positions 5 and 6 and cytosine position 5 is not a drastic lethal damage. Moreover, dehydrogenation of DNA in thymine positions 5 and 6 is not an effective mutagenic lesion. DNA dehydrogenation in cytosine position 5 has proved to be a pron...
Topics
- DNA, Fungal
- Deoxycytidine Monophosphate
- Deoxycytosine Nucleotides
- Dose-Response Relationship, Radiation
- Electrons
- Mutation
- Nucleic Acid Precursors
- Saccharomyces cerevisiae
- Thymidine Monophosphate
- Thymine Nucleotides
- Tritium