Article
Lack of mutagenicity to S. typhimurium of neopentyl bromide and pentaerythrityl tetrachloride: relation to chemical structure.
Mutation research - 1 Jan 2000
Ashby J, Callander R D, Gilman D
Abstract excerpt
Neopentyl bromide and pentaerythrityl tetrachloride were shown here to be non-mutagenic to 7 strains of Salmonella typhimurium. These inactivities are reflected in the inability of either compound to produce a colour reaction in the chemical alkylation test of Epstein (4-nitrobenzylpyridine, NBP). It is suggested that the lack of biological reactivity of these two alkyl halides is due to steric crowding of the...
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