Article
U-2973, a novel B-cell line established from a patient with a mature B-cell leukemia displaying concurrent t(14;18) and MYC translocation to a non-IG gene partner.
European journal of haematology - 1 Sept 2008
Boström Hans, Leuchowius Karl-Johan, Hallböök Helene, Nordgren Ann, Thörn Ingrid, Thorselius Mia, Rosenquist Richard, Söderberg Ola, Sundström Christer
Abstract excerpt
B-cell lymphomas/leukemias with simultaneous t(14;18)(q32;q21) and MYC rearrangements have recently been shown to constitute a separate diagnostic entity, presenting with a rapid clinical course and a very poor prognosis. We describe the establishment of an Epstein-Barr virus negative cell line, designated U-2973, from a male patient with a de novo aggressive B-cell lymphoma/leukemia and very high peripheral...
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