Article
The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage.
Nature - 1 Jan 2000
Kreiswirth B N, Löfdahl S, Betley M J, O'Reilly M, Schlievert P M, Bergdoll M S, Novick R P
Abstract excerpt
Toxic shock syndrome (TSS) is a complex of generalized symptoms caused by a local staphylococcal infection, and a circulating toxin is thought to be involved. Indeed, nearly 100% of TSS isolates produce an exoprotein, TSSE, that is thought to have an aetiological role on the basis of positive animal tests (refs 1,2 and F. Quimby, personal communication) and human serological data. Although the precise role of...
Topics
- Animals
- Exotoxins
- Genes
- Genotype
- Humans
- Immunodiffusion
- Lysogeny
- Shock, Septic
- Staphylococcus Phages
- Staphylococcus aureus