Toxic shock syndrome toxin 1 is encoded by a variable genetic element.

doi:10.1093/clinids/11.supplement_1.s83

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Article

Toxic shock syndrome toxin 1 is encoded by a variable genetic element.

Reviews of infectious diseases - 1 Jan 2000

Kreiswirth B N, Projan S J, Schlievert P M, Novick R P

Abstract excerpt

The primary cause of toxic shock syndrome is toxic shock syndrome toxin 1 (TSST-1), a 22,049-dalton exotoxin. Approximately 20% of Staphylococcus aureus isolates produce TSST-1; the production of this toxin is therefore a variable genetic trait. The TSST-1 gene and its flanking sequences are found on a genetic element that is present in TSST-1-positive isolates and absent in TSST-1-negative isolates. Preliminary...

Topics

Animals
Bacterial Toxins
Bacterial Typing Techniques
Blotting, Southern
Chromosome Mapping
DNA Probes
DNA, Bacterial
Enterotoxins
Genes, Bacterial
Genetic Variation
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nucleic Acid Hybridization

Phenotype

Polymorphism, Restriction Fragment Length

Restriction Mapping

Staphylococcus aureus

Superantigens

Source

Open in PubMed

Identifiers

PMID: 2564693
DOI: 10.1093/clinids/11.supplement_1.s83

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2564693-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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