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Article

Presumed Intraductal Papillary Mucinous Neoplasms in Individuals at High Risk for Pancreatic Cancer.

JAMA network open - 1 Sept 2026

Dall'Olio Tommaso, Capurso Gabriele, Terrin Maria, De Luca Raffaele, Coluccio Chiara, Arcangeli Valentina, Milanetto Anna Caterina, Butturini Giovanni, Fantin Alberto, Barresi Luca, De Marchi Giulia, Galli Andrea, Di Marco Marco, Panzuto Francesco, Sassatelli Romano, Ricci Claudio, Di Matteo Francesco Maria, Spinelli Elide, Dal Buono Arianna, Patruno Margherita, Cavestro Giulia Martina, Venturini Elisa, Arcidiacono Paolo Giorgio, Salvia Roberto, Falconi Massimo, Carrara Silvia, Archibugi Livia, Paiella Salvatore

Abstract excerpt

Importance: Pancreatic cystic lesions are common during surveillance of individuals at hereditary risk for pancreatic cancer, but whether their incidence and progression differ across genetic risk groups remains uncertain. Objective: To compare the incidence, morphologic characteristics, and progression of presumed intraductal papillary mucinous neoplasms (IPMNs) in individuals at high risk of PC across...

Read the complete abstract on PubMed

Topics

Humans
Female
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Pancreatic Neoplasms

Male

Incidence

Italy

Cohort Studies

Pancreatic Intraductal Neoplasms

Disease Progression

Genetic Predisposition to Disease

Risk Factors

Aged

Carcinoma, Pancreatic Ductal

Source

Open in PubMed Open full text

Identifiers

PMID: 42776526
DOI: 10.1001/jamanetworkopen.2026.35610
PMCID: PMC13602011

Genes

AHR
PC
ATM
BRCA1
BRCA2
CDKN2A
PALB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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