Data-driven serum cytokine and chemokine phenotypes are associated with MRI-defined disc regression and persistent radicular pain in lumbar disc herniation.

Abstract excerpt

Background: Inflammation after lumbar disc herniation (LDH) may contribute to radicular pain while also participating in resorption of herniated disc material. Whether circulating immune profiles are associated with these endpoint-specific recovery patterns remains uncertain. Methods: This single-center observational cohort included patients with symptomatic LDH treated between 1 January 2023 and 30 November...

Topics

• Humans
• Intervertebral Disc Displacement
• Female
• Magnetic Resonance Imaging
• Cytokines
• Male