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Article

Operational phenotyping for chronic low back pain: a narrative review and methodology for developing routing and escalation pathways across spine care.

Annals of palliative medicine - 1 Jul 2026

Lewandrowski Kai-Uwe, Pumberger Matthias, Schomig Friederike, Harhangi Biswadjiet Sanjay, Vaccaro Alexander R, Lorio Morgan P

Abstract excerpt

BACKGROUND AND OBJECTIVE: Chronic low back pain (CLBP) is clinically heterogeneous and generates substantial symptom burden, functional limitation, psychological distress, work disability, and health-care utilization. Existing phenotyping approaches often describe subgroups but do not specify how subgroup assignment changes routing, conservative-care dose, imaging, interventional escalation, surgical evaluation,...

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PMID: 42576467
DOI: 10.21037/apm-2026-1-0026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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