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Article

Exploratory Toxicogenomic Profiling Identifies Candidate DINCH-Responsive Genes Relevant to Prostate Cancer.

International journal of molecular sciences - 27 Aug 2026

Chang Chi-Fen, Lin Wen-Hsin, Huang Chao-Yuan, Yu Chia-Cheng, Lin Victor C, Lu Te-Ling, Huang Shu-Pin, Bao Bo-Ying

Abstract excerpt

Diisononyl cyclohexane-1,2-dicarboxylate (DINCH), a non-phthalate plasticizer adopted as a safer alternative for food-contact and medical-grade materials, is ubiquitously detected in human biomonitoring studies. Despite widespread exposure, its transcriptional effects in prostate cells and the potential prostate cancer relevance of DINCH-responsive genes remain unclear. We integrated transcriptomic profiling of...

Read the complete abstract on PubMed

Topics

Male
Humans
Prostatic Neoplasms
Polymorphism, Single Nucleotide
Gene Expression Regulation, Neoplastic
Gene Expression Profiling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Toxicogenetics

Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 42737583
DOI: 10.3390/ijms27177686
PMCID: PMC13566863

Genes

FAM111B
LPP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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