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Integrating genomic and exposomic data identifies endocrine disruptors potentially associated with chronic obstructive pulmonary disease.

Human genomics - 4 Feb 2026

Hong Yanggang, Song Sihan, Wang Yirong, Shu Wanyi, Dong Jinduo, Ge Xiangting

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a complex disorder driven by both genetic susceptibility and environmental exposures. Endocrine-disrupting chemicals (EDCs) are widespread environmental contaminants that interfere with hormonal and immune pathways, yet their molecular links to COPD remain insufficiently defined. METHODS: We integrated exposomic and genomic data to systematically...

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Identifiers

PMID: 41639929
DOI: 10.1186/s40246-026-00908-z
PMCID: PMC12937556

Genes

MAP1LC3B
TCF19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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