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Article

High Immunological Activity and the Re-Evaluation of Anti-SSA/SSB Antibodies as Prognostic Markers for Major Organ Damage in Systemic Lupus Erythematosus.

International journal of rheumatic diseases - 1 Sept 2026

Fang Yao-Fan, Tsai Ping-Han, Chang Che-Tzu, Chen Yen-Fu

Abstract excerpt

OBJECTIVE: Anti-SSA antibodies are among the most prevalent autoantibodies in systemic lupus erythematosus. While their association with cutaneous manifestations and neonatal lupus is established, their prognostic utility regarding long-term survival and major organ damage in adult SLE remains controversial, particularly in Asian populations. Furthermore, the added prognostic value of anti-SSB antibodies in...

Read the complete abstract on PubMed

Topics

Humans
Female
Retrospective Studies
Male
Adult
Antibodies, Antinuclear

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Lupus Erythematosus, Systemic

Risk Factors

Prognosis

Biomarkers

Middle Aged

Time Factors

Predictive Value of Tests

SS-B Antigen

Taiwan

Kidney Failure, Chronic

Lung Diseases, Interstitial

Disease Progression

Source

Open in PubMed Open full text

Identifiers

PMID: 42735434
DOI: 10.1111/1756-185x.70870
PMCID: PMC13574494

Genes

SSB
C3

Provenance

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