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Pan-genomics and multi-omics for deciphering genetic variation and accelerating genetic improvement in ruminant livestock.

Functional & integrative genomics - 11 Sept 2026

Jilo Diba Dedacha, Abebe Belete Kuraz, Ullah Waheed, Guo Juntao, Wang Jianfang, Ma Haobin, Yiheng Liu, Cheng Gong, Cui Huanhuan, Zan Linsen

Abstract excerpt

Livestock reference genomes have transformed the discovery of variants associated with production, reproduction, health, and environmental adaptation. Nevertheless, a single linear reference represents only one mosaic haplotype and incompletely captures sequence diversity within a species, particularly structural variants, copy-number changes, repeat-rich regions, and breed-specific sequences. Pangenomes address...

Read the complete abstract on PubMed

Topics

Animals
Multiomics
Genomics
Genetic Variation
Livestock
Ruminants

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Identifiers

PMID: 42726296
DOI: 10.1007/s10142-026-02042-4

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