A comprehensive water buffalo pangenome reveals extensive structural variation linked to population-specific signatures of selection.

Abstract excerpt

BACKGROUND: Water buffalo is a cornerstone livestock species in many low- and middle-income countries, yet major gaps persist in its genomic characterization-complicated by the divergent karyotypes of its two subspecies (swamp and river). Such genomic complexity makes water buffalo a particularly good candidate for the use of graph genomics, which can capture variation missed by linear reference approaches....

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