Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Sheep pan-genome retrieves the lost sequences and genes during domestication and selection.

Genomics - 1 May 2025

Liu Jiaxin, Mo Dongxin, Luo Lingyun, Shi Yilong, Xu Songsong

Abstract excerpt

The reference genome plays a crucial role in uncovering genomic variations, which increase our understanding of the molecular mechanisms influencing biological traits. However, most of the sheep reference genomes derive from a single individual, which couldn't adequately represent the genetic diversity of sheep. The map-to-pan strategy was used to construct the sheep pan-genome based on 801 samples with short...

Topics

Animals
Domestication
Sheep
Genome
Polymorphism, Single Nucleotide
Selection, Genetic
Phylogeny
Whole Genome Sequencing
Sheep, Domestic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40258447
DOI: 10.1016/j.ygeno.2025.111047

Genes

CALHM6
GPR146
GZMH
NFE2L3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sheep pan-genome retrieves the lost sequences and genes during domestication and selection.PMID 40258447Read ↗

A sheep pangenome reveals the spectrum of structural variations and their effects on tail phenotypes.Semantic proximity Read ↗

Whole genome sequencing revealed genetic diversity, population structure, and selective signature of Tianhua mutton sheep.Semantic proximity Read ↗

Whole-genome resequencing of Dorper and Hu sheep to reveal selection signatures associated with important traits.Semantic proximity Read ↗

Telomere-to-telomere sheep genome assembly identifies variants associated with wool fineness.Semantic proximity Read ↗

Genome-wide detection of structural variation in some sheep breeds using whole-genome long-read sequencing data.Semantic proximity Read ↗

Whole-genome sequence analysis unveils different origins of European and Asiatic mouflon and domestication-related genes in sheepSemantic proximity Read ↗

High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia.Semantic proximity Read ↗

Whole-Genome Sequencing Reveals Breed-Specific SNPs, Indels, and Signatures of Selection in Royal White and White Dorper SheepSemantic proximity Read ↗

Genome-wide genetic diversity and differentially selected regions among Suffolk, Rambouillet, Columbia, Polypay, and Targhee sheep.Semantic proximity Read ↗

Genome-wide analysis provides insights into the conservation status and the genomic architecture of Gentile di Puglia sheep, a Merino-type breed.Semantic proximity Read ↗

Whole-Genome Resequencing of Worldwide Wild and Domestic Sheep Elucidates Genetic Diversity, Introgression, and Agronomically Important Loci.Semantic proximity Read ↗

Whole-genome resequencing of wild and domestic sheep identifies genes associated with morphological and agronomic traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.