Article
The role of SYNE1/2 variants as a potential predisposition factor for the onset of endometriosis.
Frontiers in immunology - 1 Jan 2026
Santin Aurora, Pegoraro Silvia, Toffoli Miriam, Pianigiani Giulia, Balduit Andrea, Zito Gabriella, Mangogna Alessandro, Trevisiol Paola, Rosso Lara Emily, Mannino Federica, Di Lorenzo Giovanni, Rossi Francesca, Andreuzzi Eva, Agostinis Chiara, Ricci Giuseppe, Bulla Roberta, Girotto Giorgia
Abstract excerpt
Endometriosis (EM) is a chronic, inflammatory gynaecological disorder defined by the presence of endometrial-like tissue outside the uterine cavity, most frequently affecting the ovaries, peritoneum, and uterosacral ligaments. Despite its prevalence and the significant impact on life quality, EM is often underdiagnosed, with an average delay of about nine years, particularly affecting adolescents and young women....
Read the complete abstract on PubMedTopics
- Humans
- Female
- Endometriosis
- Nerve Tissue Proteins
- Genetic Predisposition to Disease