Article
Major histocompatibility complex class II deficiency in Morocco: a 26-year retrospective cohort study.
Frontiers in immunology - 1 Jan 2026
Kattra Aziza Bachir, Ailal Fatima, Benhsaien Ibtihal, Rada Noureddine, Admou Brahim, Hazime Raja, Benajiba Noufissa, El Hafidi Naima, Hbibi Mohamed, Hida Moustapha, Rkain Maria, El Boussaadni Yousra, Oulmaati Abdellah, Bousfiha Ahmed Aziz, El Bakkouri Jalila
Abstract excerpt
Major histocompatibility complex class II (MHC-II) deficiency is a rare autosomal recessive combined immunodeficiency caused by defects in transcriptional regulators controlling HLA class II expression. The disorder is more prevalent in North Africa due to high rates of consanguinity and founder effects. Updated national data remain limited (in Morocco, up-to-date national data on this deficit remain limited). We...
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- Humans
- Morocco
- Female
- Retrospective Studies
- Male