Article
MHC Class II Deficiency: Clinical, Immunological, and Genetic Insights in a Large Multicenter Cohort.
The journal of allergy and clinical immunology. In practice - 1 Sept 2024
Gulec Koksal Zeynep, Bilgic Eltan Sevgi, Topyildiz Ezgi, Sezer Ahmet, Keles Sevgi, Celebi Celik Figen, Ozhan Kont Aylin, Gemici Karaaslan Betul, Sefer Asena Pinar, Karali Zuhal, Arik Elif, Ozek Yucel Esra, Akcal Omer, Karakurt Leman Tuba, Yorgun Altunbas Melek, Yalcin Koray, Uygun Vedat, Ozek Gulcihan, Babayeva Royala, Aydogmus Cigdem, Ozcan Dilek, Cavkaytar Ozlem, Keskin Ozlem, Kilic Sara Sebnem, Kiykim Ayca, Arikoglu Tugba, Genel Ferah, Gulez Nesrin, Guner Sukru Nail, Karaca Neslihan Edeer, Reisli Ismail, Kutukculer Necil, Altintas Derya Ufuk, Ozen Ahmet, Karakoc Aydiner Elif, Baris Safa
Abstract excerpt
BACKGROUND: Major histocompatibility complex class II deficiency, a combined immunodeficiency, results from loss of HLA class II expression on antigen-presenting cells. Currently, hematopoietic stem cell transplantation stands as the sole curative approach, although factors influencing patient outcomes remain insufficiently explored. OBJECTIVES: To elucidate the clinical, immunologic, and genetic profiles...
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