Refractory gastroesophageal reflux-related cough: Mechanistic insights and a rational pathway to phenotype-driven management.

Abstract excerpt

This narrative synthesis proposes a hypothesis-generating, phenotype-stratified management algorithm for refractory GERC based on available evidence and clinical experience; prospective multicenter validation is needed to confirm its generalizability and long-term clinical efficacy. Gastroesophageal reflux-induced cough (GERC) accounts for 10-21% of chronic cough cases, with up to 43-75% presenting without...

Topics

• Humans
• Gastroesophageal Reflux
• Phenotype
• Chronic Cough
• Algorithms
• Cough