Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Optimizing the Cost-Effective Evaluation of Gastroesophageal Reflux by Typical Symptom Phenotypes After Failure of Empiric Acid Suppression Trial.

The American journal of gastroenterology - 1 Mar 2026

Shah Eric D, Gyawali C Prakash, Chan Walter W

Abstract excerpt

INTRODUCTION: Concern for gastroesophageal reflux disease (GERD) is the most common reason to consult gastroenterology. We aimed to optimize routine GERD evaluation on cost-effectiveness according to the dominant typical symptom among patients with persistent symptoms failing empiric proton-pump inhibitors (PPI). METHODS: We developed a decision analytic model evaluating all permutations of GERD diagnostics...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cost-Benefit Analysis
Share to Decision Support Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gastroesophageal Reflux

Share to Phenotype

Share to Proton Pump Inhibitors

Share to Quality-Adjusted Life Years

Share to Treatment Failure

Source

Open in PubMed Open full text

Identifiers

PMID: 40471840
DOI: 10.14309/ajg.0000000000003576
PMCID: PMC12354272

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Optimizing the Cost-Effective Evaluation of Gastroesophageal Reflux by Typical Symptom Phenotypes After Failure of Empiric Acid Suppression Trial.PMID 40471840Read ↗

GERD phenotypes from pH-impedance monitoring predict symptomatic outcomes on prospective evaluation.Semantic proximity Read ↗

Personalized Approach in the Work-up and Management of Gastroesophageal Reflux Disease.Semantic proximity Read ↗

White Paper AGA: Optimal Strategies to Define and Diagnose Gastroesophageal Reflux Disease.Semantic proximity Read ↗

Optimal management of severe symptomatic gastroesophageal reflux disease.Semantic proximity Read ↗

Proton Pump Inhibitors in Gastroesophageal Reflux Disease: Friend or Foe.Semantic proximity Read ↗

Adult and paediatric GERD: diagnosis, phenotypes and avoidance of excess treatments.Semantic proximity Read ↗

The American Foregut Society endoscopic classification outperforms Hill in phenotyping the esophago-gastric junction to guide gastroesophageal reflux disease management.Semantic proximity Read ↗

The Effects of Advanced Diagnostic Methods and Disease Phenotypes on the Response to PPI in Patients with Gastroesophageal Reflux Disease.Semantic proximity Read ↗

ESOPHAGEAL ACID AND SYMPTOM FREQUENCY IN GERD PHENOTYPES: A QUADRANT-BASED ANALYSIS OF SUBJECT-LEVEL VARIATIONSemantic proximity Read ↗

Cost-Utility Analysis of CYP2C19 Genotype Detection for Selection of Acid-Suppressive Therapy with Lansoprazole or Vonoprazan for Patients with Reflux Esophagitis in China.Semantic proximity Read ↗

Personalized anti-reflux surgery: connecting GERD phenotypes in 690 patients to outcomes.Semantic proximity Read ↗

Genetic variations in medical versus surgical patients with GERD: beyond PPIs and fundoplications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.