A new core-genome MLST approach for Chlamydia trachomatis genomic surveillance and research.

doi:10.1038/s41467-026-77098-8

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Article

A new core-genome MLST approach for Chlamydia trachomatis genomic surveillance and research.

Nature communications - 27 Aug 2026

Lodhia Zohra, Mixão Verónica, Isidro Joana, Ferreira Rita, Cordeiro Dora, Correia Cristina, João Inês, Pereira Joana, Gomes João Paulo, Borrego Maria José, Borges Vítor

Abstract excerpt

Chlamydia trachomatis causes common sexually transmitted infections. The use of whole-genome sequencing for its classification and surveillance is limited due to technical challenges and the lack of standardized typing frameworks. In particular, core-genome multilocus sequence typing (cgMLST), a scalable and portable approach widely applied to other bacterial pathogens, remains little explored for C. trachomatis....

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Identifiers

PMID: 42665588
DOI: 10.1038/s41467-026-77098-8
PMCID: PMC13524934

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