Integrated Analysis of the STING1-IRF1 Signaling Pathway and Genomic Alterations in Breast Cancer: Implications for Immune Evasion and Patient Prognosis.

Abstract excerpt

BACKGROUND: The STING1-IRF1 axis plays a crucial role in sensing innate immunity within the tumor microenvironment. However, the genomic landscape of this axis and its clinical implications in breast cancer still require a deeper understanding, more comprehensive explanation, and greater detail. METHODS: This study adopted a multi-cohort integrated analytical approach. Gene expression and clinical survival data...

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