Natural variation and uORF engineering complementary routes to improve ascorbic acid accumulation in tomato.

doi:10.1093/plphys/kiag583

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Natural variation and uORF engineering complementary routes to improve ascorbic acid accumulation in tomato.

Plant physiology - 4 Aug 2026

Wang Jiaying, Xie ZiYan, Zheng Hankai, Tang Huaiqian, Zhang Yuyang, Wang Taotao, Zhang Junhong, Ye Zhibiao, Ye Jie

Abstract excerpt

Ascorbic acid (AsA) determines fruit nutritional quality and antioxidant capacity in tomato, but available genetic resources for its improvement are limited. Here, we integrated natural variation analysis with upstream open reading frames (uORFs) editing to identify and engineer determinants of AsA accumulation. A natural variant in GGP2 was significantly associated with fruit AsA content, leading to the...

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PMID: 42659404
DOI: 10.1093/plphys/kiag583

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