Retinal microstructural alterations as early phenotypes of depression in radiogenomics analysis.

Abstract excerpt

BACKGROUND: With the increasing prevalence of depression, there is an urgent clinical need for early screening in depression. The retina offers a promising window for early screening in depression due to its rapid, non-invasive, objective, eye-brain correlated characteristics, but previous research has yielded conflicting alterations in retinal microstructure in depression. METHODS: We screened retinal optical...

Topics

• Humans
• Female
• Mendelian Randomization Analysis
• Phenotype
• Male
• Magnetic Resonance Imaging