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Article

Plasma metabolomics in infancy reveals early signatures of a stringently-defined otitis-prone phenotype.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Aug 2026

Prince Nicole, Chen Jing, Kaur Ravinder, Syphurs Caitlin, Hoch Annmarie, Angelidou Asimenia, McEnaney Kerry, Chawes Bo, Bæk Ole, Wang Tingting, Brustad Nicklas, Levy Ofer, Diray-Arce Joann, Pichichero Michael, Lasky-Su Jessica A

Abstract excerpt

BACKGROUND: Otitis media is highly prevalent during early life, yet the molecular factors that predispose children to recurrent episodes are poorly defined. Metabolomics captures dynamic biochemical changes and may help identify pathways influencing otitis susceptibility. We examined whether longitudinal infant plasma metabolomic profiles were associated with development of stringently-defined otitis proneness in...

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Biomarkers
Chromatography, Liquid
Cohort Studies
Longitudinal Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tandem Mass Spectrometry

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PMID: 42608976
DOI: 10.1111/pai.70428
PMCID: PMC13482141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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