Article
Exploring the Varied Clinical Presentation of Pediatric Asthma through the Metabolome.
American journal of respiratory and critical care medicine - 1 May 2025
Mendez Kevin M, Kachroo Priyadarshini, Prince Nicole, Huang Mengna, Cote Margaret, Chu Su H, Chen Yulu, Sharma Rinku, Hecker Julian, Chen Liang, Gerszten Robert, Clish Clary, Avila Lydiana, Celedón Juan C, Wheelock Craig E, Weiss Scott T, McGeachie Michael, Broadhurst David I, Kelly Rachel S, Reinke Stacey N, Lasky-Su Jessica A
Abstract excerpt
Rationale: Pediatric asthma is heterogeneous, with varied clinical presentations and treatment responses. Metabolomic profiling may uncover shared and unique biological mechanisms across clinical traits that characterize pediatric asthma. Objectives: To characterize the varied clinical presentation of pediatric asthma by examining the metabolome's relationship with 22 clinical traits, categorized into five...
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