Diabetes-associated diffuse myocardial fibrosis assessed by native T1 mapping: Adverse cardiac phenotype and modest incremental prognostic value in a real-world cohort.

doi:10.1016/j.ijcard.2026.134730

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Article

Diabetes-associated diffuse myocardial fibrosis assessed by native T1 mapping: Adverse cardiac phenotype and modest incremental prognostic value in a real-world cohort.

International journal of cardiology - 15 Nov 2026

Treiber Julia M, Backhaus Sören J, Wolter J Sebastian, Handrick Judith, Unbehaun Claudia, Kriechbaum Steffen, Rieth Andreas, Puntmann Valentina, Nagel Eike, Keller Till, Sossalla Samuel, Rolf Andreas

Abstract excerpt

BACKGROUND: Diabetes mellitus (DM) promotes myocardial remodeling through advanced glycation end-products, interstitial fibrosis, and microvascular dysfunction. We investigated whether native T1 mapping captures this adverse phenotype and provides incremental prognostic information beyond established clinical risk factors in a real-world population. METHODS: Patients undergoing CMR were enrolled in a prospective...

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Topics

Humans
Female
Prognosis
Male
Fibrosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Prospective Studies

Phenotype

Middle Aged

Magnetic Resonance Imaging, Cine

Aged

Cohort Studies

Myocardium

Diabetic Cardiomyopathies

Registries

Diabetes Mellitus

Follow-Up Studies

Source

Open in PubMed

Identifiers

PMID: 42600700
DOI: 10.1016/j.ijcard.2026.134730

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