Article
Coexistent Diabetes Is Associated With the Presence of Adverse Phenotypic Features in Patients With Hypertrophic Cardiomyopathy.
Diabetes care - 1 Aug 2022
Jex Nicholas, Chowdhary Amrit, Thirunavukarasu Sharmaine, Procter Henry, Sengupta Anshuman, Natarajan Pavithra, Kotha Sindhoora, Poenar Ana-Maria, Swoboda Peter, Xue Hui, Cubbon Richard M, Kellman Peter, Greenwood John P, Plein Sven, Page Stephen, Levelt Eylem
Abstract excerpt
OBJECTIVE: Type 2 diabetes mellitus (T2DM) is associated with worsened clinical outcomes in hypertrophic cardiomyopathy (HCM) patients. We sought to investigate whether HCM patients with T2DM comorbidity exhibit adverse cardiac alterations in myocardial energetics, function, perfusion, or tissue characteristics. RESEARCH DESIGN AND METHODS: A total of 55 participants with concomitant HCM and T2DM (HCM-DM) (n =...
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