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Article

Impact of oral contraceptives and metformin on advanced lipid phenotyping in polycystic ovary syndrome.

European journal of endocrinology - 3 Aug 2026

Lee Iris T, Soffer Daniel E, Remaley Alan T, Playford Martin P, Mehta Nehal N, Coutifaris Christos, Legro Richard S, Dokras Anuja

Abstract excerpt

CONTEXT: Combined oral contraceptives (OCPs) and metformin are commonly used in patients with polycystic ovary syndrome (PCOS), who are at elevated risk of dyslipidemia and cardiovascular disease (CVD), but their effects on advanced lipid phenotyping remain unclear. OBJECTIVE: To examine the impact of OCPs and metformin on (1) lipoproteins, (2) apolipoproteins, and (3) cholesterol efflux capacity (CEC, marker of...

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PMID: 42592843
DOI: 10.1093/ejendo/lvag149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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