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Article

Polygenic and Pleiotropic Adaptation of Yaks to High Altitudes: A Genome-Wide Study of Hematological and Physiological Traits.

Animal genetics - 1 Aug 2026

Sun Guangming, Liu Ziqi, Jiang Hui, Li Xin, Zhang Hui, Ouzhuluobu, Qi Xuebin, Basangwangdui, Ge Siyu, Wang Yiming, Zheng Wangshan, Zhu Yanbin

Abstract excerpt

Hematological adaptation is critical for oxygen transport at high altitudes. While hemoglobin concentration is well-studied, yak (Bos grunniens) hematology versus lowland cattle remains under-explored. We analyzed blood phenotypes from 1244 plateau yaks and 154 lowland cattle. Yaks exhibited elevated hemoglobin, hematocrit, and lymphocyte counts, but reduced platelet counts and monocyte/neutrophil percentages...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42578654
DOI: 10.1002/age.70175
PMCID: PMC13459750

Genes

SLIT3
FSTL5
PCDH15
CDH13
PRIM2

Provenance

PubMed metadata and Literature Corpus relationships.

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