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Article

Paper microfluidic implementation of loop mediated isothermal amplification for early diagnosis of hepatitis C virus.

Nature communications - 30 Nov 2021

Witkowska McConnell Weronika, Davis Chris, Sabir Suleman R, Garrett Alice, Bradley-Stewart Amanda, Jajesniak Pawel, Reboud Julien, Xu Gaolian, Yang Zhugen, Gunson Rory, Thomson Emma C, Cooper Jonathan M

Abstract excerpt

The early diagnosis of active hepatitis C virus (HCV) infection remains a significant barrier to the treatment of the disease and to preventing the associated significant morbidity and mortality seen, worldwide. Current testing is delayed due to the high cost, long turnaround times and high expertise needed in centralised diagnostic laboratories. Here we demonstrate a user-friendly, low-cost pan-genotypic assay,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34848705
DOI: 10.1038/s41467-021-27076-z
PMCID: PMC8632961

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