Article
Molecular subtyping of adrenocortical carcinoma reveals distinct subtypes with prognostic and therapeutic implications.
Endocrine-related cancer - 1 Aug 2026
Wu Luming, Su Tingwei, Zhang Cui, Jiang Lei, Xie Jing, Zhou Weiwei, Jiang Yiran, Zhong Xu, Wang Weiqing
Abstract excerpt
Adrenocortical carcinoma (ACC) is a rare but aggressive malignancy with poor survival and limited treatment options. To comprehensively characterize its molecular landscape and identify clinically relevant subtypes, we performed an integrated genomic analysis - including whole-exome sequencing, RNA sequencing, and copy number variation profiling - on 61 Chinese patients with ACC. We identified recurrent mutations...
Topics
Join the communities discussing this publication.