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Identification and validation of a tumor mutation burden-related signature combined with immune microenvironment infiltration in adrenocortical carcinoma.

Mathematical biosciences and engineering : MBE - 12 May 2022

Luo Yong, Chen Qingbiao, Lin Jingbo

Abstract excerpt

Tumor mutation burden (TMB), an emerging molecular determinant, is accompanied by microsatellite instability and immune infiltrates in various malignancies. However, whether TMB is related to the prognosis or immune responsiveness of adrenocortical carcinoma (ACC) remains to be elucidated. This paper aims to investigate the impact of TMB on the prognosis and immune microenvironment infiltration in ACC. The...

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Adrenal Cortex Neoplasms
Adrenocortical Carcinoma
Biomarkers, Tumor
Killer Cells, Natural
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Microenvironment

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PMID: 35730296
DOI: 10.3934/mbe.2022333

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