Urban heat island and risk of rheumatoid arthritis: Insights from genetic predisposition and proteomics.

doi:10.1016/j.jaut.2026.103606

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Article

Urban heat island and risk of rheumatoid arthritis: Insights from genetic predisposition and proteomics.

Journal of autoimmunity - 1 Sept 2026

Zhang Zhenao, Gao Shunbing, Hu Xue, Sun Xiaoya, Wang Ziyi, Zhang Jiejun, Yang Yuetong, Ren Jingyi, Ma Yuxia

Abstract excerpt

BACKGROUND: Urban heat island (UHI) exposure is an increasingly common consequence of urbanization and climate warming, but its association with rheumatoid arthritis (RA) risk remains unclear. OBJECTIVE: To investigate the association between UHI exposure and incident RA, and to further assess the roles of genetic susceptibility and plasma proteomic profiles in this association. METHODS: This study included...

Read the complete abstract on PubMed

Topics

Humans
Arthritis, Rheumatoid
Genetic Predisposition to Disease
Proteomics
Female
Male

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Risk Factors

Middle Aged

Genetic Risk Score

Urban Population

Adult

Hot Temperature

Aged

Source

Open in PubMed

Identifiers

PMID: 42546420
DOI: 10.1016/j.jaut.2026.103606

Genes

CD40
SUGP1
VCAM1

Provenance

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