Article
Prioritization of deleterious mutations informs genomic prediction and increases the rate of gain in common bean (Phaseolus vulgaris L.), a simulation study.
TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik - 3 Aug 2026
Cordoba-Novoa H, Hoyos-Villegas V
Abstract excerpt
KEY MESSAGE: Predicted deleterious mutations (SNPs) have different distributions of effects compared to random SNPs based on population composition. Variant prioritization of markers based on deleterious scores can improve the prediction of yield. Favoring mating schemes between parents with fewer highly deleterious mutations can increase the rate of genetic gain. The study of mutations is fundamental to...
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