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Type 5 Diabetes Mellitus: Pathophysiology, Clinical Phenotype, and Nutritional Management.

Diabetes/metabolism research and reviews - 1 Sept 2026

Şahin Anılgan İrem Nur, Atar-Uğurlu Aslıhan

Abstract excerpt

Type 5 Diabetes Mellitus (T5DM) is an emerging diabetes phenotype linked to chronic undernutrition. It predominantly affects young, lean individuals in low- and middle-income countries. After its formal recognition by the International Diabetes Federation in 2025, T5DM resurfaced as a clinically relevant insulin-deficient phenotype. It is now viewed as distinct from classical autoimmune and insulin-resistant...

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PMID: 42531222
DOI: 10.1002/dmrr.70212
PMCID: PMC13422767

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