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Exploratory identification of coding and splicing-related SNV variants in A1A1 and A2A2 β-casein Holstein dairy cows.

Journal of animal science - 8 Jan 2026

Jiménez-Montenegro Lucía, Urrutia Olaia, Cánovas Ángela

Abstract excerpt

The A2 β-casein variant has gained considerable interest in the dairy industry due to proposed health-related benefits, leading to an increasing frequency of the A2A2 genotype in dairy herds. Although the A1/A2 substitution in the β-casein gene (CSN2) does not directly affect gene regulation, previous transcriptomic studies have reported differences in mRNA isoform expression between A1A1 and A2A2 cows....

Topics

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Caseins
Cattle
Gene Expression Regulation
Glycolipids
Glycoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 42528265
DOI: 10.1093/jas/skag233
PMCID: PMC13461648

Genes

ABCG2
ACSL1
ATP10A
ATP11B
ATP5PF
COX7A2
CSN2
DBNL
EIPR1
FASN
LPIN1
MFGE8
NDUFAB1
NDUFV2
SEC31A
SPTLC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Exploratory identification of coding and splicing-related SNV variants in A1A1 and A2A2 β-casein Holstein dairy cows.PMID 42528265Read ↗

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