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Variant discovery in the sheep milk transcriptome using RNA sequencing.

BMC genomics - 15 Feb 2017

Suárez-Vega Aroa, Gutiérrez-Gil Beatriz, Klopp Christophe, Tosser-Klopp Gwenola, Arranz Juan José

Abstract excerpt

BACKGROUND: The identification of genetic variation underlying desired phenotypes is one of the main challenges of current livestock genetic research. High-throughput transcriptome sequencing (RNA-Seq) offers new opportunities for the detection of transcriptome variants (SNPs and short indels) in different tissues and species. In this study, we used RNA-Seq on Milk Sheep Somatic Cells (MSCs) with the goal of...

Topics

Animals
Dairying
Female
Gene Expression Profiling
Genetic Variation
Milk
Molecular Sequence Annotation
Quantitative Trait Loci
Sequence Analysis, RNA
Sheep

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PMID: 28202015
DOI: 10.1186/s12864-017-3581-1
PMCID: PMC5312585

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