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The central role of DNA damage in immunosenescence

3 Jul 2023

Abstract excerpt

Ageing is the biggest risk factor for the development of multiple chronic diseases as well as increased infection susceptibility and severity of diseases such as influenza and COVID-19. This increased disease risk is linked to changes in immune function during ageing termed immunosenescence. Age-related loss of immune function, particularly in adaptive responses against pathogens and immunosurveillance against...

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PMID: 37465119
DOI: 10.3389/fragi.2023.1202152

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