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Article

Causal effects of gut microbiota on physical growth and cognitive performance via plasma metabolites: A Mendelian randomization study.

Medicine - 24 Jul 2026

Yang Fang-Fang, Luo Kai-Peng, Liang Zhi-Jie, Ou Zhuo-Xin, Li Sheng-Lan, Liang Jia-Mei, Lin Yu-Nan

Abstract excerpt

Herein, we used plasma metabolites as potential mediators to determine the causal relationship between gut microbiota, cognitive performance, and physical growth. The relationship between gut microbiota and these 3 factors has not been accurately established in human experiments and studies; our study may provide some new insights. Two-sample Mendelian randomization was performed to evaluate causal associations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42499064
DOI: 10.1097/MD.0000000000049865
PMCID: PMC13406128

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