Article
Genetic and molecular approaches for patients with familial hemophagocytic lymphohistiocytosis: a multi-center experience from Mexico.
Frontiers in immunology - 1 Jan 2026
Gutiérrez-Guerrero Arturo, Lugo-Reyes Saul O, López-Rivera Daniela Olivia, Sánchez-Herrera Jacqueline, Valenzuela-Vázquez Lucero, Estevez-Mieres Mercy, Nuñez Nuñez Maria Enriqueta, Bayardo-Gutiérrez Beatriz, Lona-Reyes Juan Carlos, Cruz-Osorio Rosa Margarita, Soto-Chavez Veronica, Bedolla-Barajas Martín, Gutierrez-Hernández José Alonso, Barragan-Arevalo Tania, Hidalgo-Martinez Maria Fernanda, Gomez-Cardenas Liliana, Sierra-Muñoz Diego, Perea Alvarez Samantha, Venegas-Montoya Edna, Staines-Boone Aide Tamara, Zarate-Hernández Maria Del Carmen, Miranda-Saavedra Vania Maria, Arce-Estrada Gabriel Emmanuel, Scheffler-Mendoza Selma, Bustamante-Ogando Juan Carlos, Llamas-Guillén Beatriz Adriana, Ruiz-Fernández Miguel, Reynoso-Arenas Perla Veronica, Flores-Munguía Martín Eduardo, Torres-Lozano Carlos, Bonal-Pérez Miguel Angel, Mamani-Velásquez Estefany Graciela, Martínez-Barricarte Rubén, Ramírez-Uribe Rosa María Nideshda, Pastor Nina, Martinez-Duncker Ivan, Gaytan Paul, Yañez Jorge A, Yamazaki-Nakashimada Marco Antonio, Lenoir Christelle, Latour Sylvain, Espinosa Sara Elva, Cruz-Munoz Mario Ernesto
Abstract excerpt
Introduction: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition that results from a severe inflammation caused by an exaggerated immune response. HLH may have a genetic cause affecting the proper function of cytotoxic immune cells or it canbe linked to other pathological settings including inborn errors of immunity, malignancies, autoinflammatory and autoimmune syndromes, metabolic...
Read the complete abstract on PubMed